Adult patients of childbearing age with moderate to strong symptoms of uterine fibroids, for whom symptom-orientated treatment (with progestins or ulipristal acetate) or invasive treatment is the best course of therapy. Appropriate comparator therapy: Patient-specific therapy depending on type and severity of symptoms as well as the burden on the patient. Selection of: observation, symptom orientated treatment such as, progestins taking into account the respective approval status (for patients where symptomatic treatment of the prolonged and/or heavy menstrual bleeding is sufficient), or ulipristal acetate (for patients who are have not reached menopause and those for which an embolisation of uterine fibroids and/or surgery has failed or is not suitable); or invasive treatment options.